Can you add mods to a existing save?

[EezyTarget]

I've been playing vanilla for a couple of months and I am enjoying the game and have started a new game with mods for the first time. Currently I've only got Nanobots. Is it possible to add mods to my current save or do I have to start again with the mods installed first?

[darkfrei]

Make a copy of your save file and play we what you will with the new one. Some mods are comfortable for every mod, but some are incompatible.

[Loewchen]

You can add and remove mods as you like, for mods that fundamentally change vanilla gameplay it would not be practical though.