One issue i'm having, it's minor, but it's quite annoying to me, is power lines.
I don't know if i'm just bad at placing them, or it becomes less of an issue later in the game (i've only put in a few hours so far) but i find that i end up with power poles dotted around my map with wires criss crossing my equipment willy-nilly.
It's frustrating to have to arrange poles to get to the one unpowered inserter in a group of buildings and i end up with wires crossing over all over the place. It's frustrating and distracts me from concentrating on making my automation stuff work (which is a struggle for me atm while i'm learning

Is there any plans to change this?
The ideal situation (i think) would be to have buildings and equipment 'transfer' power to adjacent blocks. So if you have a clump of equipment sitting next to each other, you only need to run a power line to the first item and the whole group will then be powered.