
then the inserter will not take items from multiple slots - it will only take 2 items from the first slot, even though it could take 2 more from the next slot.
This is relevant when loading trains using chests as a buffer, like this:

Sometimes the first slot of the chest will get one item in it, and then that item gets loaded onto the train by itself (instead of 4 items at a time), and then another item comes into the chest, and gets loaded by itself, etc... which can make it take much longer to load the train.