I had what I thought was a temporary issue with my Gleba science production. I cleared the issue (thank you remote view!) and thought everything was fine. I checked back a couple of minutes later just to be sure and the factory was about to shut down starved of nutrients. My bioflux to nutrient biochamber was backed up on spoilage... not just the output slot, but the bioflux input. I manually cleared it (thank you again remote view!) but nope that wasn't enough. It seems that the inserters removing spoilage only remove spoiled outputs. If the input bioflux (or mash for producing the bioflux) is on the point of spoiling, the inserters will pick it up and insert it, but then it spoils before it can be used... and sits there, blocking the inserters from inserting any fresh ingredients and halting production.
Now the obvious solution is not to have any issues so the factory keeps working, using ingredients before they spoil I have added a couple of alarms, because you can at least read the contents and send an alarm if the contents are spoiled, but it would be lovely to have a way to automatically remove spoiled inputs. Or at least spoiled inputs that are not intended to be spoiled looking at you sulfur!
My own personal Factorio super-power - running out of power.