I don't know if it is even possible without losing ones mind. The factory has to be huge, and to be able to handle a LOT of resources. the biggest resource eaters would be roboports (45k advanced circuits and steel alone), T3 factories, rocket defense and modules of course. And there may be a lot of crazy expensive things that I don't recall at the moment.
Hunting fish should also be frustrating as hell

What do you guys think? Could that be a thing?