The entire setup is rather massive and vastly expensive for just a minor savings of uranium ore, but the largest offender is that the fluorine cost isn't worth it in the slightest. The best way to go about this is providing fluorite waste water after the creation of the hexaflourite with a 90% return so it's moderately self-sustainable and not wasteful.
The entire setup is very expensive in both power and materials overall, so self-sustainability is critical when the gains aren't worth the constant cost of power and materials. This helps make it costly to get it started but much more tolerable to run over a prolonged period of time, just as the uranium power mod was designed to be. However, constantly paying this high cost destroys the entire chain and makes uranium ore alone far superior.
I've got some visual representations to support this, which are all based on my per minute process of 570 uranium cycles.
-----
Just a small sample of the requirements for hexaflourite (Including the sulfate recycling!)
Chain
Uranium ore alone
Chain
It's quite extensive and complicated in its own right, but when you also factor in the Angels ores required to make the essentials, you start to really notice the heavy cost.
Fluorite + Uranium ore
Recipe
Uranium alone
Recipe
Far cheaper by a long shot, even without all the other processing materials on top of it. So that's something else to add to your list to reconsider the balance for to make it more worthwhile.
