Good Morning!
After playing for pretty much the entire night i feel that a bugreport is warranted, although i have trouble pinpointing the cause for the bug. Several production lines seem to suffer breakdowns for no apparent reason.
In each case over the course of several hours there was a Chemical Plant involved in the production. I'll try to describe as best as possible:
In the case in the screenshot there are two chem plants producing engine parts and engines. Both got all ressources (including lubricant) needed for the production, still there are some major hick-ups. In the screenshot the assembly with the Iron Gear Wheels isn't producing, although there are Iron Plates available (it worked fine for hours but suddenly stopped, without making any modifications to the building or surrounding area). The same thing happend to the chem plant earlier, all ressources were available, but production would come to a sudden halt for no apparent reason.
This also happend on another Chem Plant producing sulfur... in that case i used a buffer chest between the sulfur and the sulfuric acid plant which seems to fix the problem. So my best guess is that the chemplants have trouble making the "call" to delivering inserters/factorys when running out of ressources. It seems that this effect can even "jump" to any other assembly/chem plant that is delivering goods to it.

edit: left the game runing in the background, no change. Saving and reloading did empty the chemplants of all lubricant, but the bug still is there. Noticed that the tooltip says the the plant is missing lubricant, although there are 200 units available:
