You are right. Interesting that Shift+Left Click does not work on the icon within the tech tree, but it does work on the "Start research" button. I did not consider that the button may have different behavior than the icon.

Hello-

Use Case
When in editor mode, it is useful to test out builds with only a certain number of technologies researched. To do so, I open the editor and unresearch the technologies I don't want enabled that might affect a build. For example, inserter stack size is affected by "Inserter ...