TL;DR
ZERO-G-ASSEMBLY : unique upgrade modules for buildings that do not have regular module slots.What ?
We already have upgrade modules and such, but with that never implemented space mechanics there is a golden opportunity to utilize new assembling process. ZERO-G-ASSEMBLY.You'll be able to build zero-g-assembly TM assembler that could produce things that are not produceable on normal planet. First you need some asteroid material (mineable in space in orbit where you move around with space ship car).
You can then research new science pack (zero-g-science) produced in space and hauled back from space. With that you can research new upgrade slots.
Modules such as roboport range increase, roboport charge rate increase. Unique +1 module slot upgrade or maybe even +100% speed power use module that you can not put into beacon. But you may produce upgrade for beacon that allows it to have 3 module slots!
But beware once you reach space aliens will notice it and start next phase of their evolution bringing more resistant and stronger biters spitters and now flyers! So you hopefully stacked some upgrades before going for a space walk.