This can be seen when rotating a chemical plant, as the inputs will rotate clockwise while the sprite rotates anticlockwise. (Most apparent by paying attention to the vat of green goo.)
Here's an image to show what I mean.
![Image](http://i.imgur.com/jbTw5PC.png?1)
This doesn't appear to be just me as, looking through videos and screenshots, it goes back as far as the trailer.