Hey I been living with this one for a while, always figured it was some issue on my specs end, maybe the factory too big, but It isnt.
Every so often the game would freeze, and unfreeze, movement is preserved over the time, so a item on a belt will skip forward a bit.
I found a fix though, I simply changed the multi-sampling setting, and it went away. But changing it up not just down stopped this, so it must have something to do with the rendering side of things.
So yea, it doesnt seem to matter what my graphical settings are, factory size or anything, random stuttering would occur, changing the multi-sampling (Only option i changed, tested many times) fixes it for that session.
[0.11.22] Slight intermittent freezes
Re: [0.11.22] Slight intermittent freezes
There have been multiple improvements to the graphics library Factorio uses in 0.12 and I believe this issue to be resolved. If it happens again in 0.12 please post and let us know.
If you want to get ahold of me I'm almost always on Discord.