Unfortunately I can't, and it's occurring on both of the machines I have (Lenovo Thinkpad X1E and my desktop). It happens a ton when trying to save. Really unfortunate, I'll keep trying every few months and hopefully I can play again eventually.

I assume this means you aren't able to resolve this? This is(was I guess) my favorite game, but it's basically unplayable for me now.

log 4
534.028 Error CrashHandler.cpp:492: Exception Code: c0000005, Address: 0x00007ff6ff1ad516
ModuleBase: 0x00007ff6ff080000, ImageSize: 01d63000, RelativeAddress: 0012d516
534.028 Error CrashHandler.cpp:498: Access Violation: Read at address FFFFFFFFFFFFFFFF
534.028 Error CrashHandler.cpp:512 ...

files....
8079.098 Error CrashHandler.cpp:492: Exception Code: c0000005, Address: 0x00007ff6ff388924
ModuleBase: 0x00007ff6ff080000, ImageSize: 01d63000, RelativeAddress: 00308924
8079.098 Error CrashHandler.cpp:498: Access Violation: Read at address FFFFFFFFFFFFFFFF
8079.098 Error CrashHandler.cpp ...

log 3 and save file

it does it with my other playthrough as well.

log 2
196.315 Info AppManager.cpp:306: Saving to _autosave3 (blocking).
196.364 Verbose Scenario.cpp:878: Saving game as C:\Users\mccar\AppData\Roaming\Factorio\saves/_autosave3
196.412 Info LuaGameScript.cpp:786: level state size: 1157 bytes.
196.413 Info LuaGameScript.cpp:786: mod ...

This started happening a few months ago and I'm just getting around to reporting (just happened to me 3x in 20 minutes). The game will crash randomly, often times, but not exclusively, during saves which then corrupts the save file. This happens with the game in focus, in the background, while doing ...