I just wanted to note that this issue did resolve upon the installation of the newest nvidia drivers 390.59

I ended up deciding to just goto one monitor whenever I want to play this. Rolling back the driver wants to remove a bunch of other packages that I need and I don't want to sort all of that out. I'm going to keep an eye on this and if the next 390.x driver release has the same problem I'll make a ...

NVIDIA seems to be the one to blame:
https://forums.factorio.com/viewtopic.php?f=7&t=59282#p355893
Nice, I don't know how I missed that in my previous searches. These recent nvidia driver releases have had a number of different issues but I thought the last one was good, I guess think again! I'll ...

I want to mention that I actually stopped using xinerama multihead configuration for a specific reason and not only because it is generally not the preferred method these days. I ran into this problem (I am "neder" here).
https://github.com/MrAlex94/Waterfox/issues/510
So I am basically in a ...

The game will not launch at all, all I see is the little "Preparing to launch.." window appear for a second and then in the library next to Factorio it says "Running" for about 20 seconds before that disappears as well. Any help would be appreciated, I've spent about three hours on this and the only ...