Dealing with the biters and nests is not an issue. :-) I can destroy lots of nests without any issue, even if there are a lot of worms..
I try to describe what really annoys me: My base is huge so I try to - let's say expand it at the south-west. I destroy all enemy bases and the area is clear. Now ...
I created a new freeplay game with the option activated "Enemies never attack first."
Now I want to change that option for my save game. Is there any possibility to activate auto attacks of the enemies again?