The mod issue is a problem with uploading my save after finishing the game.
Something about missing Chartbundle files from a mod.
Thank you for helping me out with my stupid PC issues.

Further testing after a restart shows that I am now able to send the platform off without any issues.
No crashes, no bluescreens.
I apologize for the trouble.
I will talk to the mod author so I can get my save uploaded without issue.

Some good news, some bad news.
After saving my game I re-enabled the autosave for first travel.
Then I loaded into the copy I downloaded for the bug submission.
It had no issues autosaving and beginning the run to the system edge.
So I then exited the game and then made a copy of the non-testing ...

I have not tried that yet.
I managed to get to the system edge after disabling the autosave and I found a new issue relating to a mod.
I will restart my PC and see if that fixes both issues.
The other issue is a mod issue and I will let the mod author know.

Yes, I am able to load back into the same save before I hit travel, then when the autosave triggers it crashes.
Do you need me to create some more logs for you to work with?

Currently without any mod setting changes, mod removals, or setting changes:
The game will crash whenever I tell one of my platforms to go to the System Edge from Aquilo orbit for the first time.
The game will pause for the autosave, the progress bar will go about 1/4th of the bar length, then the ...