Thanks for the report. I am considering this to be a duplicate of https://forums.factorio.com/116465 as you have modified bindings. In this case having pipette on middle click causes ambiguity on the quickbar because usually middle click is used for clearing filter and you have it bound to pipette ...

What did I do?

Play the game in any mode. Enter the "Tips and Tricks" menu. Click on "Entity pipette". (With everything unlocked, it is the 4th item in the list.) Finally, watch the scenario play out.

What happened?

After roughly 11 seconds, the scenario crashes. (The game continues to work ...