Happenend again today with the same map/game just with a older save from 2 hours before the last savefile.
See Log attached.

Also did a memcheck today - RAM seems completely fine

And is it possible to fix this Savefile manually to continue playing this Savegame?

Hi, thanks for the reply.
No probably not, but I checked all the other Savefiles of this game and non would load, even older ones that were 15 min before the crash.

Game out of nowhere during playing. Now loading the last auto-save instantly crashes the game again.
Bug log and save game are attached.
factorio-current.log:
Last Autosave: