Deleting that file fixed the issue. Thank you for your assistance.

I run an older MacOS version - 10.14.6 - due to compatibility with some other apps and the fact my laptop is from 2015. Have been able to use Factorio without issue before, to the point of running a megabase at one point.

Installed Space Age and went up to 2.0.8 today, but Factorio crashed almost ...