Can you update to Afterburner 4.2.0 with RivaTuner Statistics Server 6.4.0/6.4.1 and see if the problem still occurs?
Apparently H1Z1 had the same problem after an update (crash on startup / very soon ingame) and updating the RTSS to 6.4.0 fixed the issue.

Updated to the below - no crashes yet ...

From MSI Afterburner 4.1.1.7625 - not overclocking:

CPU
________________________________________________________________________________
Model : Intel(R) Core(TM) i7-2600K CPU @ 3.40GHz
Logical cores : 8
CPUID : GenuineIntel family 6, model 2A, stepping 7
Tjmax : 98°C

GPU1 ...

posila wrote:Correct. I have tried it on several HW configurations already with no crashes. I am starting to think a cause of the crashes is not overlay but rather overclocked or somehow "fine tuned" GPU.

I don't have any overclocking - I do have the afterburner overlay.

Thanks for the help! But I really hope overlay support is added before too long, I use the steam overlay to chat to people while playing a lot, and I feel kind of nervous playing any game without my GPU temperature on screen, since my graphics card is finnicky and prone to random overheating.
If ...

Raiden333 wrote:

Raiden333 wrote:I'll try deleting everything related to Factorio on my PC and re-installing it via steam.

Is there anything outside of the folders in %appdata% and the old Factorio install location that I may need to remove?

daniel34 wrote:If you have the MSI Afterburner overlay (or any other third-party overlay) enabled, disable them.

I don't have any overlays enabled (even the Steam overlay), and I still have the issue if I don't force to 0.12.22.

In the beta selection in Steam, forcing it to 0.12.22 seems to fix the issue.

I have exactly the same symptoms