I couldn't find a reference to similar posts using search.
It doesn't seem to be a feature in https://wiki.factorio.com/Keyboard_bindings - I don't see this as a feature, if you want to blow all your inventory up do what everyone else does and put it in a box and blow that up!
SHIFT + Left mouse button in inventory on items invokes destructor
Re: SHIFT + Left mouse button in inventory on items invokes destructor
Do you have logistic robots researched? Maybe items are transferred to the Trash slots?