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RIght now i have red clips and machine gun and car to go fight the nests....but i it is too much for big nests....
and the bugs seems to get bigger and bigger more hours i play
I stil have turrets with clips inside....but I am afraid that will not be enough soon....
do the nests spread or they stay at the same place, so when you kill the nest it is over they do not multiply
what is the best way to destroy nests'

They are indeed getting stronger aka biter evolution, which is affected by 3 factors time, pollution and spawner kills. (the wiki can explain it better: https://wiki.factorio.com/Enemies)
The nests expand from time to time, if you have biter expansion enabled. That can be switched off at map gen, if you select different settings. default settings are somewhat tough, if you first play the game.

There are multiple methods to kill nests. heavy armour, shotgun and grenades is very effective early game. also turret creep works.
for bullets, physical projectile damage is very important to reduce costs.
flamethrowers with walls are very good for defence.
car and tank helps clearing nests. red ammo is very expensive and is better used against bigger biters
with power armour you have many, many more options...

The car is fine for early game. Once you have blue science you get the tank, which makes you a lot more robust until you get power armor, shields and laser defenses later.
The rocket launcher can be helpful when you get it as it has a lot of range. The flamethrower can do a lot of damage against groups. Poison capsules are good too

Early game turret creep is the standard for larger nests. Bullets are competitive throughout the game. You just need to research the shooting speed and damage upgrades. They are particularly effective for turrets as you get a bonus for both the turret and the bullets

do the nests spread or they stay at the same place

Depends on your map settings. Standard is that they expand.

My personal playslyle is certainly not for everyone, and once you're at the point you're at, it may be impossible to do now, but perhaps not.

I run an extremely minimal factory to start, and watch my pollution closely. If pollution reaches the nearest nest, I shut down whatever factory is polluting in that direction. I might also go kill the nest. Basically I rush solar panels, and do a lot of hand crafting. Once I have solar, I deconstruct steam power, so my factory only runs in the day. Then I push research, and build walls and gun turrets far out to prevent biters moving too close. I feed the turrets from yellow belt with yellow inserters, which uses less power, is cheaper to build, and has the added benefit of showing the number of yellow inserters in power usage, so you know exactly how many gun turrets you have in your wall. Once I have a massive area walled off, I crank up production, harden the wall, switch turrets to red ammo, and cover the entire walled area with roboports and scanners, so the wall auto-repairs. Once you have nuclear power, you can add laser turrets to your wall.

In your situation, I would turn off power to your entire base, and gather all resources from all belts. Possibly deconstruct everything and build just a central turret nest. Start hand-crafting ammo, walls, and some turrets, and manually keep your turrets loaded, if you have mined ore and are running out of metal, consider manually loading the ore into furnaces, but watch your pollution. Don't mine more unless you're desperate, if you have to, you're probably doomed. Nests should stop attacking once the pollution no longer touches them. Then slowly start up again, and switch over to solar.