Where I am really looking to get advice is how to deal with all these new methods of production and tips/ideas/suggestions for setting up my base so that there's some rhyme and reason to the madness.
Set up the angels ore processing AWAY from the main bus, and give it PLENTY of space. as you need to process 6 different raw ores, each of which can easily take up 20 tiles of width (or height, if you set it up that way), you need to reserve 120 tiles of width, and...crushing->floatation->chemical refining->thermal refining->Sorting is 5 steps, with around 20-30 tiles for each step, so 150 tiles tall, except you'll also want 6-8 tiles extra in each so you can bring the products to a special sorting zone later on, so reserve yourself a whopping 190 tiles of height. (you need the extra width if you don't know what you're doing so you can squeeze in some of the chemical production, such as flouric acid, where it's needed rather than finding yourself without a remotely convenient place to put it). You might not actually need that much space, since you'll want to chuck beacons at it anyways, but it's definitely better to reserve too much space for the ore processing than too little. Indeed, you may not desire to make a full setup at all...but again; it's better to have that space and not need it than to have to redo your entire ore processing just becuase you didn't reserve enough space.
You may need to have a separate crush and smelt area to get yourself started. Note that for any process other than crushing and smelting, you will always sort it before smelting it. Ideally, you will never have to move the sorting machines if you set up your stuff correctly. Bob's inserter configuration mod will really help here.
Reserve an area near the ore processing for slag and geode processing (these two interact a little bit; note that all of this needs lots of water), and an even bigger area reserved for angels refining (to multiply ore output if you desire it).
Reserve a giant area for angels refining. POint the output of the ore processing towards it.
Use wood as your source of plastic so you can just use the treefarm for it.
Use a one-sided bus so that you can expand the bus as needed.
You will get tons of sulfur once you start your slag processing up, as long as you recycle the sulfur waste water (also known as yellow waste water). You can get some sulfur water from most ore floatation to get yourself started, and can safely ignore most sources of sulfur.
You will also want to leave room for multiple purified water pipes coming in, as flotation demands lots of water once you really get going.
You'll not need to bus iron ore beyond the smelters/refineries, not even for ferric chloride; you only need a little bit of iron for it. One inventory of iron ore should last you until you get robots up and running.
You probably won't want to bus most of the gears or other exotic components like bearings; if you really need a few tier 2 miners, for instance, just handcraft them, build them on-site, or wait till bots.
Most of the things which use ferric chloride to produce have very similar other things they use, so you can produce these on the same branch of the factory.
Angels petrochems makes rocket fuel complicated enough to have a dedicated fluid bus all to itself.
You'll want to bot a lot of the gases like chlorine and hydrogen chlorine once you can, becuase otherwise you'll have to pipe them. However, most gases and fluids do not need to go on the main bus; the main exceptions are ferrich chloride, and maybe sulfuric acid and/or hydrochloric acid.
Get squeak through, and maybe far reach. This is a hard enough modpack combination WITHOUT needing to worry about what you can or cannot walk through.
Mendel wrote:I would really recommend adding factorissimo to your mods if you have not already. It makes it much easier to make things less messy.
So basically you get stuff out of your bus with splitters and underground belts, resources go into factorissimo factory building, you set up assemblers and stuff in the factory and then end products come out of the factory. Makes things much cleaner and less messy.
I have an example save game in this thread
viewtopic.php?f=18&t=35207. Its not perfect as it is my first attempt at bob´s but maybe you might get some idea or two out of it. Maybe even bad ideas. Its still quite messy and I could make it much cleaner by adding a few more factorissimo factories here and there. (If I would start over I would probably also only make the bus 2-3 lines per resource, not 4)
basically you then just expand your factory in small chunks. first set up basic electronics components, then go more advanced one step at a time with more and more advanced things assembled in factorissimos further up the belt.
just keep in mind you can only build 255(?) of them before running out of "layers" and crashing the game. with a modpack like this, going over that limit wouldn't be hard.