Factorio Forums

If you press the "Sync Mods and Load Game" button (after restarting the game), then later, for example, if you disable the mods and manually restart the game (without pressing the "Sync Mods and Load Game" button again), the game will attempt to load automatically again.

Thanks for the report. I started looking into this, and due to the nature of program arguments and restarting I don't currently see a good way to address this.